Response to "Unexpected mutations after CRISPR-Cas9 editing in vivo"
Nat Methods
.
2018 Apr;15(4):235-236.
doi: 10.1038/nmeth.4559.
Epub 2018 Mar 30.
Authors
Lauryl M J Nutter
1
2
,
Jason D Heaney
3
,
K C Kent Lloyd
4
,
Stephen A Murray
5
,
John R Seavitt
3
,
William C Skarnes
6
,
Lydia Teboul
7
,
Steve D M Brown
1
7
,
Mark Moore
1
Affiliations
1
IMPC Cas9 Working Group and the IMPC Steering Committee and executive director of the IMPC (www.mousephenotype.org).
2
The Centre for Phenogenomics, The Hospital for Sick Children, Toronto, Canada.
3
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA.
4
Mouse Biology Program, University of California, Davis, Davis, California, USA.
5
The Jackson Laboratory, Bar Harbor, Maine, USA.
6
The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, USA.
7
Mammalian Genetics Unit, Medical Research Center (MRC) Harwell Institute, Harwell, UK.
PMID:
29600991
DOI:
10.1038/nmeth.4559
No abstract available
Publication types
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Comment
MeSH terms
CRISPR-Cas Systems*
Clustered Regularly Interspaced Short Palindromic Repeats*
Gene Editing
Mutation
Grants and funding
MC_U142684172/MRC_/Medical Research Council/United Kingdom
MC_UP_1502/3/MRC_/Medical Research Council/United Kingdom
UM1 OD023221/OD/NIH HHS/United States
UM1 OD023222/OD/NIH HHS/United States