Safety of laparoscopic fundoplication in children under 5 kg: a comparative study

Surg Endosc. 2018 Oct;32(10):4191-4199. doi: 10.1007/s00464-018-6164-6. Epub 2018 Mar 30.

Abstract

Background: Laparoscopic fundoplication in children under 5 kg is still debated. Our objective was to evaluate the safety and efficacy of laparoscopic fundoplication (LF) in children under 5 kg.

Methods: We reviewed the cases of 96 children treated by laparoscopic fundoplication between 2005 and 2014. Thirty-five patients had a weight of 5 kg or less at the time of LF (Low Weight Group) and 61 patients had a weight between 5.1 and 10 kg (High Weight Group). The pre-operative, peri-operative, post-operative data regarding surgery and anesthesia were compared between groups.

Results: Mean weight was 3.9 ± 0.8 kg in the LWG and 7.8 ± 1.5 kg in the HWG. Children in the LWG were more prone to pre-operative respiratory management (40% mechanical ventilation and 42.9% oxygen therapy). The operating times (82 ± 28 min for LWG and 85 ± 31 min for HWG) and respiratory parameters during the procedure (PCO2) were comparable between groups. Post-operative complications were 1 gastric perforation with peritonitis and 1 small bowel obstruction in the LWG, 2 cases of gastric perforation with peritonitis in the HWG. Mean follow-up was 67 ± 44 months. Significant recurrence of GERD requiring a redo fundoplication was noted in 3 patients in the LWG and 1 patient in the HWG.

Conclusion: Laparoscopic fundoplication is a safe procedure in infants ≤ 5 kg without increase of post-operative complications, recurrence, or mean operative time.

Keywords: Children; Fundoplication; Laparoscopic; Morbidity; Prematurity; Safety.

Publication types

  • Comparative Study
  • Observational Study

MeSH terms

  • Body Weight*
  • Child, Preschool
  • Female
  • Follow-Up Studies
  • Fundoplication / methods*
  • Gastroesophageal Reflux / surgery*
  • Humans
  • Infant
  • Infant, Newborn
  • Laparoscopy*
  • Male
  • Patient Safety
  • Postoperative Complications / epidemiology
  • Postoperative Complications / etiology
  • Recurrence
  • Retrospective Studies
  • Treatment Outcome