Leukocytoclastic Vasculitis and Desensitization to High-dose Methotrexate in Primary Central Nervous System Lymphoma

Clin Lymphoma Myeloma Leuk. 2018 May;18(5):e197-e200. doi: 10.1016/j.clml.2018.03.008. Epub 2018 Mar 19.

Authors

Colette Hanna¹, Diego Villa², Carla Irani³, Marwan Ghosn¹, Elie El Rassy⁴

Affiliations

¹ Department of Hematology-Oncology, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon.
² Division of Medical Oncology, BC Cancer - Vancouver, and Centre for Lymphoid Cancer, Vancouver, BC, Canada.
³ Department of Internal Medicine, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon.
⁴ Department of Hematology-Oncology, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon. Electronic address: [email protected].

PMID: 29605422
DOI: 10.1016/j.clml.2018.03.008

No abstract available

Keywords: HD ARA-C; HD MTX; High-dose methotrexate; Hypersensitivity; Lymphoma.

Publication types

Case Reports

MeSH terms

Antimetabolites, Antineoplastic / administration & dosage*
Antimetabolites, Antineoplastic / adverse effects
Antimetabolites, Antineoplastic / immunology
Central Nervous System Neoplasms / drug therapy*
Central Nervous System Neoplasms / pathology
Central Nervous System Neoplasms / physiopathology
Desensitization, Immunologic*
Dose-Response Relationship, Drug
Humans
Lymphoma, B-Cell / drug therapy*
Lymphoma, B-Cell / pathology
Lymphoma, B-Cell / physiopathology
Male
Methotrexate / administration & dosage*
Methotrexate / adverse effects
Methotrexate / immunology
Middle Aged
Premedication
Treatment Outcome
Vasculitis, Leukocytoclastic, Cutaneous / chemically induced
Vasculitis, Leukocytoclastic, Cutaneous / pathology
Vasculitis, Leukocytoclastic, Cutaneous / prevention & control*

Substances

Antimetabolites, Antineoplastic
Methotrexate

Supplementary concepts

Erythema elevatum diutinum