Malignant Solitary Fibrous Tumor Metastatic to Widely Invasive Hurthle Cell Thyroid Carcinoma: A Distinct Tumor-to-Tumor Metastasis

Int J Surg Pathol. 2018 Sep;26(6):521-524. doi: 10.1177/1066896918767321. Epub 2018 Apr 4.

Abstract

We illustrate a case of synchronous malignant solitary fibrous tumor of the thoracic cavity, and widely invasive thyroid Hurthle cell carcinoma. The Hurthle cell carcinoma was found to harbor distinct areas of malignant solitary fibrous tumor. This is a unique case of tumor-to-tumor metastasis that, to the best of our knowledge, has not been previously reported.

Keywords: Hurthle cell carcinoma; NAB2-STAT6; STAT6; dedifferentiated solitary fibrous tumor; follicular carcinoma; malignant solitary fibrous tumor; metastasis; sarcoma; thyroid.

Publication types

  • Case Reports

MeSH terms

  • Adenoma, Oxyphilic / diagnostic imaging
  • Adenoma, Oxyphilic / pathology
  • Adenoma, Oxyphilic / secondary*
  • Adenoma, Oxyphilic / surgery
  • Biomarkers, Tumor / analysis
  • Biopsy, Fine-Needle
  • Humans
  • Neoplasms, Multiple Primary / diagnostic imaging
  • Neoplasms, Multiple Primary / pathology*
  • Neoplasms, Multiple Primary / surgery
  • Oxyphil Cells / pathology
  • Pleura / pathology
  • Pleura / surgery
  • Pleural Neoplasms / pathology*
  • Positron Emission Tomography Computed Tomography
  • Solitary Fibrous Tumors / pathology
  • Solitary Fibrous Tumors / secondary*
  • Solitary Fibrous Tumors / surgery
  • Thyroid Gland / diagnostic imaging
  • Thyroid Gland / pathology
  • Thyroid Neoplasms / diagnostic imaging
  • Thyroid Neoplasms / pathology
  • Thyroid Neoplasms / secondary*
  • Thyroid Neoplasms / surgery

Substances

  • Biomarkers, Tumor

Supplementary concepts

  • Thyroid cancer, Hurthle cell