LRRK2 kinase in Parkinson's disease

Science. 2018 Apr 6;360(6384):36-37. doi: 10.1126/science.aar5683.
No abstract available

MeSH terms

  • Animals
  • Communicable Diseases / complications
  • Communicable Diseases / genetics
  • Genes, Dominant
  • Humans
  • Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 / genetics*
  • Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 / metabolism
  • Mice
  • Mutation, Missense
  • Parkinson Disease / etiology
  • Parkinson Disease / genetics*
  • Phosphorylation
  • Signal Transduction
  • rab GTP-Binding Proteins / metabolism

Substances

  • Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
  • RAB8A protein, human
  • rab GTP-Binding Proteins