Exercise and Sinonasal Disease

Immunol Allergy Clin North Am. 2018 May;38(2):259-269. doi: 10.1016/j.iac.2018.01.014. Epub 2018 Mar 2.

Abstract

Physical exercise requires proper function of the upper and lower airways in order to meet exertional ventilatory requirements. Athletes performing frequent intensive exercise experience more sino-nasal symptoms and demonstrate objective decreases in sino-nasal function when compared with the general population. Sino-nasal dysfunction is known to interfere with sport performance. Nasal epithelial injury, neutrophilic influx, and decreased mucociliary clearance have been associated with intensive training. In this review, the authors provide a comprehensive overview of the prevalence of sino-nasal disease in athletes, the possible underlying pathophysiologic mechanisms, and a summary of diagnostic and treatment options.

Keywords: Chronic rhinosinusitis; Exercise-induced rhinitis; Nasal hyperreactivity; Nasal obstruction; Rhinitis; Upper airway disease.

Publication types

  • Review

MeSH terms

  • Athletes / statistics & numerical data*
  • Chronic Disease / epidemiology
  • Chronic Disease / prevention & control
  • Doping in Sports / prevention & control
  • Exercise / physiology*
  • Glucocorticoids / pharmacology
  • Glucocorticoids / therapeutic use
  • Histamine Antagonists / pharmacology
  • Histamine Antagonists / therapeutic use
  • Humans
  • Immunotherapy / methods
  • Nasal Mucosa / drug effects
  • Nasal Mucosa / immunology
  • Nasal Mucosa / physiopathology
  • Performance-Enhancing Substances / pharmacology
  • Performance-Enhancing Substances / therapeutic use
  • Prevalence
  • Rhinitis / diagnosis
  • Rhinitis / epidemiology*
  • Rhinitis / etiology
  • Rhinitis / therapy
  • Sinusitis / diagnosis
  • Sinusitis / epidemiology*
  • Sinusitis / etiology
  • Sinusitis / therapy

Substances

  • Glucocorticoids
  • Histamine Antagonists
  • Performance-Enhancing Substances