Lung Ultrasound and Microbubbles Enhance Aminoglycoside Efficacy and Delivery to the Lung in Escherichia coli-induced Pneumonia and Acute Respiratory Distress Syndrome

Am J Respir Crit Care Med. 2018 Aug 1;198(3):404-408. doi: 10.1164/rccm.201711-2259LE.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aminoglycosides / administration & dosage*
  • Animals
  • Anti-Bacterial Agents / administration & dosage*
  • Disease Models, Animal
  • Drug Delivery Systems / methods*
  • Escherichia coli Infections / drug therapy
  • Gentamicins / administration & dosage
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Microbubbles*
  • Pneumonia, Bacterial / drug therapy*
  • Respiratory Distress Syndrome / drug therapy*
  • Ultrasonic Waves*

Substances

  • Aminoglycosides
  • Anti-Bacterial Agents
  • Gentamicins

Grants and funding