Liver Doppler Findings in Pediatric Patients After Total Pancreatectomy and Islet Autotransplantation

J Ultrasound Med. 2018 Nov;37(11):2595-2601. doi: 10.1002/jum.14617. Epub 2018 Apr 15.

Abstract

Objectives: This study was intended to establish normal values for velocities in the hepatic artery and portal veins in pediatric patients after total pancreatectomy and islet autotransplantation (TPIAT).

Methods: A retrospective review was performed of liver Doppler studies in pediatric patients after TPIAT over 6 years at an academic children's hospital. Doppler velocities in the liver vasculature and the hepatic artery resistive index were recorded.

Results: Sixty-five pediatric patients were evaluated. There were no cases of portal vein thrombosis or other hepatic vascular complications. The mean hepatic artery peak systolic velocity was 157.6 cm/s (SE, 60.9 cm/s), with a mean resistive index of 0.57 (SE, 0.09). The mean main portal vein velocity was 31.9 cm/s (SE, 12.9 cm/s).

Conclusions: Portal vein thrombosis is rare in pediatric patients after TPIAT. A wide range of hepatic artery and portal vein velocities are encountered in children immediately after TPIAT without hepatic vascular complications and can be considered normal.

Keywords: Doppler; Doppler (abdominal); islet autotransplantation; islet cell; pancreatectomy; pancreatitis; pediatrics.

MeSH terms

  • Adolescent
  • Blood Flow Velocity / physiology
  • Child
  • Child, Preschool
  • Female
  • Hepatic Artery / diagnostic imaging
  • Hepatic Artery / physiology*
  • Hospitals, Pediatric
  • Humans
  • Liver / blood supply*
  • Liver / diagnostic imaging
  • Liver / physiology
  • Liver Transplantation*
  • Male
  • Pancreatectomy*
  • Portal Vein / diagnostic imaging
  • Portal Vein / physiology*
  • Retrospective Studies
  • Transplantation, Autologous
  • Ultrasonography, Doppler / methods*