Channel activity of mirror-image M2 proton channel of influenza A virus is blocked by achiral or chiral inhibitors

Protein Cell. 2019 Mar;10(3):211-216. doi: 10.1007/s13238-018-0536-5.

Authors

Qing-Yan Guo¹, Long-Hua Zhang¹, Chao Zuo¹, Dong-Liang Huang¹, Zhipeng A Wang¹, Ji-Shen Zheng², Chang-Lin Tian³

Affiliations

¹ School of Life Sciences, University of Science and Technology of China, Hefei, 230027, China.
² School of Life Sciences, University of Science and Technology of China, Hefei, 230027, China. [email protected].
³ School of Life Sciences, University of Science and Technology of China, Hefei, 230027, China. [email protected].

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Amantadine / pharmacology*
Antiviral Agents / pharmacology*
Biological Transport / drug effects
Hydrogen / metabolism
Influenza A virus / metabolism*
Ion Channels / antagonists & inhibitors*
Ion Channels / chemical synthesis
Rimantadine / pharmacology*
Viral Matrix Proteins / antagonists & inhibitors*
Viral Matrix Proteins / chemical synthesis

Substances

Antiviral Agents
Ion Channels
M2 protein, Influenza A virus
Viral Matrix Proteins
Rimantadine
Hydrogen
Amantadine