Corpus callosum demyelination associated with acquired stuttering

BMJ Case Rep. 2018 Apr 21:2018:bcr2017223486. doi: 10.1136/bcr-2017-223486.

Abstract

Compared with developmental stuttering, adult onset acquired stuttering is rare. However, several case reports describe acquired stuttering and an association with callosal pathology. Interestingly, these cases share a neuroanatomical localisation also demonstrated in developmental stuttering. We present a case of adult onset acquired stuttering associated with inflammatory demyelination within the corpus callosum. This patient's disfluency improved after the initiation of immunomodulatory therapy.

Keywords: multiple sclerosis; neuroimaging; stuttering.

Publication types

  • Case Reports

MeSH terms

  • Adjuvants, Immunologic / therapeutic use
  • Adult
  • Corpus Callosum / diagnostic imaging
  • Corpus Callosum / pathology*
  • Demyelinating Diseases / diagnostic imaging
  • Demyelinating Diseases / pathology*
  • Diagnosis, Differential
  • Female
  • Glatiramer Acetate / administration & dosage
  • Glatiramer Acetate / therapeutic use
  • Humans
  • Injections, Subcutaneous / methods
  • Magnetic Resonance Imaging / methods
  • Multiple Sclerosis / blood
  • Multiple Sclerosis / cerebrospinal fluid
  • Multiple Sclerosis / diagnostic imaging*
  • Multiple Sclerosis / therapy
  • Stuttering / diagnosis*
  • Stuttering / etiology
  • Treatment Outcome

Substances

  • Adjuvants, Immunologic
  • Glatiramer Acetate