An audit of pregnancy outcomes in solid organ transplant recipients at a metropolitan hospital

Aust N Z J Obstet Gynaecol. 2019 Feb;59(1):102-104. doi: 10.1111/ajo.12815. Epub 2018 Apr 22.

Abstract

Background: Pregnancies in patients with solid organ transplants have higher rates of complications and caesarean sections (CS).

Aim: To perform an audit of the pregnancy outcomes in transplant recipients, to determine the rate of CS in our cohort, the appropriate skin incision for CS in these patients and to formulate recommendations for preoperative planning.

Materials and methods: This is a retrospective cohort study. All patients who had a solid organ transplant were identified from the obstetrics database. The operation records of the transplant recipients who delivered by CS were reviewed and the de-identified data were evaluated for pregnancy outcomes.

Results: This cohort consisted of 22 women: six had simultaneous pancreas and kidney (SPK) transplants and 16 had kidney transplants. Over a ten-year period, four women had two pregnancies and one had a twin pregnancy, thus 27 babies were born. The rate of CS was 58% (n = 15) and the surgical approach in 13 of these patients was by Pfannenstiel incision. One patient had an elective midline incision at the first CS, which was repeated in the next pregnancy. Two CS were complicated by bladder injury, both occurring in SPK recipients.

Conclusion: Patients with solid organ transplants have a higher rate of CS and SPK patients may be at a higher risk of bladder injuries during CS. Our data suggest that Pfannenstiel skin incision is still suitable for these patients. We recommend reviewing the operative details of the transplant operation and a pelvic magnetic resonance imaging for pre-operative planning.

Keywords: bladder injury; caesarean section; kidney transplant; simultaneous pancreas kidney transplant.

MeSH terms

  • Adult
  • Cesarean Section / statistics & numerical data
  • Cohort Studies
  • Female
  • Hospitals, Urban
  • Humans
  • Medical Audit
  • New South Wales / epidemiology
  • Organ Transplantation*
  • Pregnancy
  • Pregnancy Complications / epidemiology*
  • Pregnancy Complications / mortality
  • Prenatal Care*
  • Retrospective Studies
  • Survival Analysis
  • Transplant Recipients*