Immune cell infiltration in Ectomesenchymal chondromyxoid tumor: An immunohistochemical study

Oral Oncol. 2018 Jun:81:112-115. doi: 10.1016/j.oraloncology.2018.04.012.

Abstract

Ectomesenchymal chondromyxoid tumor (ECT) is a rare benign neoplasm, often affecting the anterior dorsum of the tongue. To date, approximately 74 cases of lingual ECT have been published. This report describes, for the first time, the morphological and immunohistochemical features of a unique ECT case, which revealed diffuse infiltration by immune cells with a dendritic-like appearance inside the tumor proliferation. The significance of these findings and discussion about the tumor cell-immune cell interactions are presented.

Keywords: Ectomesenchymal chondromyxoid tumor; Immunohistochemistry; Tongue neoplasm; Tumor immune infiltrate.

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Dendritic Cells / immunology*
  • Humans
  • Immunohistochemistry
  • Immunophenotyping
  • Male
  • Mesenchymoma / immunology*
  • Mesenchymoma / pathology*
  • Middle Aged
  • Tongue Neoplasms / immunology*
  • Tongue Neoplasms / pathology*