Safety assessment of biotechnologically produced 2'-Fucosyllactose, a novel food additive

Food Chem Toxicol. 2018 Aug:118:84-93. doi: 10.1016/j.fct.2018.04.049. Epub 2018 Apr 25.

Authors

Damien van Berlo¹, Alinde E Wallinga², Frederique A van Acker³, Dianne J Delsing⁴

Affiliations

¹ Triskelion BV, Utrechtseweg 48, 3700 AV Zeist, The Netherlands. Electronic address: [email protected].
² Triskelion BV, Utrechtseweg 48, 3700 AV Zeist, The Netherlands. Electronic address: [email protected].
³ Triskelion BV, Utrechtseweg 48, 3700 AV Zeist, The Netherlands. Electronic address: [email protected].
⁴ FrieslandCampina, Amersfoort, The Netherlands. Electronic address: [email protected].

PMID: 29704579
DOI: 10.1016/j.fct.2018.04.049

No abstract available

Keywords: 2′-fucosyllactose; Genotoxicity; Human milk oligosaccharide; Infant formula; Repeated dose toxicity; Safety.

MeSH terms

Animals
Dose-Response Relationship, Drug
Erythrocyte Indices
Erythrocytes
Female
Hematocrit
Hemoglobins
Humans
Lymphocytes / drug effects
Male
Milk, Human / chemistry
Mutagenicity Tests
Mutation
Rats
Rats, Wistar
Salmonella typhimurium / drug effects
Trisaccharides / administration & dosage
Trisaccharides / chemistry
Trisaccharides / metabolism*
Trisaccharides / toxicity*

Substances

Hemoglobins
Trisaccharides
2'-fucosyllactose