Background biomonitoring of residue levels of 137 pesticides in the blood plasma of the general population in Beijing

Environ Monit Assess. 2018 Apr 29;190(5):315. doi: 10.1007/s10661-018-6694-3.

Abstract

Due to the widespread use of pesticides, human exposure to pesticides is possible and can potentially cause adverse impacts on public health. We measured 137 pesticides including organophosphorus, organochlorine, pyrethroid and carbamate pesticides together with various herbicides in 100 human blood samples collected from the general population in Beijing. The samples were analysed by triple quadrupole tandem gas chromatography-mass spectrometry. In total, 24 organochlorine pesticides, 5 pyrethroid pesticides and 6 organophosphorus pesticides were detected. The detection rates of HCB, α-HCH, β-HCH, γ-HCH, p,p'-DDE and quintozene were 99, 96, 74, 72, 96 and 95%, respectively. No statistically significant gender difference in the blood concentrations of the pesticides was found. Consistent with the trend of the increasing β-HCH, p,p'-DDE and quintozene concentrations with age, a strong positive correlation between the age and concentrations of β-BHC, p,p'-DDE and quintozene was observed.

Keywords: GC-MS/MS; General population; Human blood; Pesticide.

MeSH terms

  • Beijing
  • Dichlorodiphenyl Dichloroethylene / analysis
  • Dichlorodiphenyl Dichloroethylene / blood
  • Environmental Exposure / statistics & numerical data*
  • Environmental Monitoring*
  • Environmental Pollutants / blood*
  • Female
  • Gas Chromatography-Mass Spectrometry
  • Hexachlorocyclohexane / blood
  • Humans
  • Hydrocarbons, Chlorinated / analysis
  • Male
  • Pesticide Residues / blood*

Substances

  • Environmental Pollutants
  • Hydrocarbons, Chlorinated
  • Pesticide Residues
  • alpha-hexachlorocyclohexane
  • Dichlorodiphenyl Dichloroethylene
  • Hexachlorocyclohexane
  • beta-hexachlorocyclohexane