Multiple Endocrine Neoplasia Type 2b (MEN2B) in a 9-Year-Old Female

Solon T Kao; Christopher J Capua; Rafik A Abdelsayed

doi:10.1016/j.joms.2018.03.042

Multiple Endocrine Neoplasia Type 2b (MEN2B) in a 9-Year-Old Female

J Oral Maxillofac Surg. 2018 Sep;76(9):1925-1928. doi: 10.1016/j.joms.2018.03.042. Epub 2018 Apr 7.

Authors

Solon T Kao¹, Christopher J Capua², Rafik A Abdelsayed³

Affiliations

¹ Assistant Professor, Department of Oral and Maxillofacial Surgery, Dental College of Georgia, Augusta University, Augusta, GA.
² Chief Resident, Department of Oral and Maxillofacial Surgery, Dental College of Georgia, Augusta University, Augusta, GA. Electronic address: [email protected].
³ Professor and Director of Diagnostic Laboratory, Section of Oral and Maxillofacial Pathology, Department of Oral Health and Diagnostic Sciences, Dental College of Georgia, Augusta University, Augusta, GA.

PMID: 29709408
DOI: 10.1016/j.joms.2018.03.042

Abstract

Multiple endocrine neoplasia (MEN) is an uncommon genetic syndrome transmitted as an autosomal dominant condition characterized by multiple tumors or hyperplasia of neuroendocrine tissues. MEN type 2b (MEN2B) often has clinical signs of marfanoid facial appearance and mucosal neuromas of the head. This report describes the diagnosis of MEN2B in a previously undiagnosed 9 year old who presented for biopsy of an oral lesion.

Published by Elsevier Inc.

Publication types

Case Reports

MeSH terms

Biomarkers, Tumor / blood
Biopsy
Child
Diagnosis, Differential
Female
Head and Neck Neoplasms / diagnosis*
Head and Neck Neoplasms / pathology
Head and Neck Neoplasms / surgery*
Humans
Multiple Endocrine Neoplasia Type 2b / diagnosis*
Multiple Endocrine Neoplasia Type 2b / pathology
Multiple Endocrine Neoplasia Type 2b / surgery*
Neck Dissection
Neoplasm Staging
Thyroidectomy

Substances

Biomarkers, Tumor