A New Method toward Microengineered Surfaces Based on Reactive Coating

Jörg Lahann; Insung S Choi; Jinwook Lee; Klavs F Jensen; Robert Langer

doi:10.1002/1521-3773(20010903)40:17<3166::AID-ANIE3166>3.0.CO;2-#

A New Method toward Microengineered Surfaces Based on Reactive Coating

Angew Chem Int Ed Engl. 2001 Sep 3;40(17):3166-3169. doi: 10.1002/1521-3773(20010903)40:17<3166::AID-ANIE3166>3.0.CO;2-#.

Authors

Jörg Lahann¹, Insung S Choi¹, Jinwook Lee¹, Klavs F Jensen¹, Robert Langer¹

Affiliation

¹ Department of Chemical Engineering Massachusetts Institute of Technology Cambridge, MA 02139 (USA) Fax: (+1) 617-258-8827.

PMID: 29712076
DOI: 10.1002/1521-3773(20010903)40:17<3166::AID-ANIE3166>3.0.CO;2-#

Abstract

By using chemical vapor deposition (CVD) a range of substrates can be coated with a highly reactive polymer containing pentafluorophenol ester groups. A biotin-modified pattern is generated on the substrate by microcontact printing; such a pattern interacts specifically with fluorescein-conjugated streptavidin and thereby the pattern becomes observable with fluorescence microscopy.

Keywords: CVD; cyclophanes; immobilization; microcontact printing; reactive coating.