Cell division control in Caulobacter crescentus

Justine Collier

doi:10.1016/j.bbagrm.2018.04.005

Cell division control in Caulobacter crescentus

Biochim Biophys Acta Gene Regul Mech. 2019 Jul;1862(7):685-690. doi: 10.1016/j.bbagrm.2018.04.005. Epub 2018 Apr 30.

Author

Justine Collier¹

Affiliation

¹ Department of Fundamental Microbiology, Faculty of Biology and Medicine, University of Lausanne, Quartier UNIL/Sorge, Lausanne, CH 1015, Switzerland. Electronic address: [email protected].

PMID: 29715525
DOI: 10.1016/j.bbagrm.2018.04.005

Abstract

Caulobacter crescentus is a free-living Alphaproteobacterium that thrives in oligotrophic environments. This review focuses on the regulatory network used by this bacterium to control the levels of cell division proteins, their organization inside the cell and their activity as a function of the cell cycle. Strikingly, C. crescentus makes frequent use of master transcriptional regulators and epigenetic signals, most likely to synchronize cell division with other events of the cell cycle. In addition, cellular metabolism and DNA damage sensors emerge as central players regulating cell division in response to changing environmental conditions.

Keywords: Caulobacter crescentus; Cell division; Epigenetics; Master regulators; Metabolism; Stress.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Bacterial Proteins / genetics
Caulobacter crescentus / physiology*
Cell Division*
DNA Damage
Gene Expression Regulation, Bacterial
Gene Regulatory Networks*
Stress, Physiological

Substances

Bacterial Proteins