Seroprevalence of Borrelia burgdorferi in Belgian forestry workers and associated risk factors

Parasit Vectors. 2018 May 2;11(1):277. doi: 10.1186/s13071-018-2860-2.

Abstract

Background: As forest is the preferred environment for ticks, forestry workers are exposed to tick bites and tick-borne diseases. We assessed the seroprevalence of anti-Borrelia burgdorferi (Bb) antibodies and investigated, using an integrated landscape approach, the individual and environmental factors associated with the seroprevalence of Bb in Belgian forestry workers, a high-risk group in Belgium.

Methods: A group of 310 Belgian forest workers was examined to assess the seroprevalence of anti-Borrelia IgG antibodies. Using principal component analysis and binary logistic regression, the joint effects of individual characteristics and environmental characteristics were examined.

Results: Sixty-seven of the 310 workers were seropositive for Lyme disease (LD), leading to a seroprevalence of 21.6%. The seroprevalence was higher among forest workers visiting forests more frequently (P = 0.003) or who reported over 100 tick bites (P-value < 0.001). The intensity of tick bites and the use of protection measures against tick bites have a positive impact on LD seroprevalence while the quantity of shadow from trees at ground level had a negative one.

Conclusions: This study showed that forest workers are a population at risk for LD and, by extension, at risk for various tick-borne diseases. In addition to the role of the environment, our results also showed the importance of considering exposure when predicting the risk of infection by Bb.

Keywords: Belgium; Borrelia burgdorferi; Exposed groups; Forestry workers; Lyme disease; Risk; Serology; Seroprevalence; Tick.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Animals
  • Antibodies, Bacterial / blood*
  • Belgium / epidemiology
  • Borrelia burgdorferi / immunology*
  • Female
  • Forestry*
  • Humans
  • Immunoglobulin G / blood
  • Logistic Models
  • Lyme Disease / epidemiology
  • Lyme Disease / microbiology
  • Male
  • Middle Aged
  • Occupational Exposure*
  • Principal Component Analysis
  • Risk Factors
  • Seroepidemiologic Studies*
  • Tick Bites / epidemiology
  • Tick Bites / immunology*
  • Tick Bites / microbiology
  • Tick-Borne Diseases / epidemiology
  • Tick-Borne Diseases / microbiology
  • Ticks / microbiology

Substances

  • Antibodies, Bacterial
  • Immunoglobulin G