Conservative treatment of non-aneurysmal infectious aortitis: a case report and review of the literature

Acta Clin Belg. 2019 Apr;74(2):86-91. doi: 10.1080/17843286.2018.1467586. Epub 2018 May 10.

Abstract

Background: Non-aneurysmal infectious aortitis is a rare clinical entity with most often lethal complications when surgical intervention is delayed.

Objectives: This report describes the case of a non-aneurysmal infectious aortitis complicated with a penetrating aortic ulcer in an elderly woman, caused by a methicillin-sensitive Staphylococcus aureus. Surgery was deemed contra-indicated and treatment was limited to the administration of intravenous vancomycin (2 grams daily), followed by flucloxacillin (6 times 2 grams daily). She remains well after one year.

Methods: The Internet databases Medline and Embase were searched. Articles were selected based on relevanceof abstract, article type and impact of the journal.

Results: A literature review addresses current insights in the pathogenesis, diagnosis, and treatment of non-aneurysmal infectious aortitis.

Keywords: Aortitis; elderly; infectious; non-aneurysmal; pseudoaneurysm.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged, 80 and over
  • Anti-Bacterial Agents / therapeutic use*
  • Aortitis / complications
  • Aortitis / drug therapy*
  • Aortitis / microbiology
  • Contraindications, Procedure
  • Female
  • Floxacillin / therapeutic use*
  • Humans
  • Methicillin-Resistant Staphylococcus aureus
  • Staphylococcal Infections / drug therapy*
  • Staphylococcal Infections / microbiology
  • Ulcer / microbiology
  • Vancomycin / therapeutic use*

Substances

  • Anti-Bacterial Agents
  • Floxacillin
  • Vancomycin