Acute retinal necrosis is an uncommon but devastating and potentially blinding ophthalmopathy featured with unfavorable prognosis as the lesions tend to develop rapidly in a circumferential way in few days. Therefore timely diagnosis and early treatment are of great significance. The polymerase chain reaction test on intraocular fluid can improve specificity and sensitivity of the etiological detection for acute retinal necrosis. Etiology results included in the diagnostic criteria is favorable for etiological diagnosis. Current treatment for acute retinal necrosis is generally based on systemic antiviral therapy, and supported by hormone and antithrombotic drugs, while surgical treatment should be considered when the disease progresses. This article reviews the research progress on the diagnosis and treatment of acute retinal necrosis in an effort to improve the diagnosis and treatment performance of acute retinal necrosis. (Chin J Ophthalmol, 2018, 54: 306-311).
急性视网膜坏死(ARN)是一种严重的致盲性眼病,其病程进展迅速,预后较差,常导致患者视力严重下降,甚至丧失视力,因此及时准确的诊断及早期治疗具有重要意义。ARN眼内液聚合酶链式反应检测可以提高其病原学检出的特异性及敏感性,将病原学检测结果纳入诊断标准有益于疾病的早期对因诊断。目前ARN的治疗方法以全身抗病毒治疗为主,糖皮质激素及抗血栓药物治疗为辅,病情进展可考虑手术治疗。本文将对ARN诊断及治疗的最新研究进展进行总结和分析,以期为临床提高ARN的诊断及治疗水平提供参考。(中华眼科杂志,2018,54:306-311).
Keywords: Diagnosis; Retinal necrosis syndrome, acute; Therapy.