RETRACTED: NFKB1 mediates Th1/Th17 activation in the pathogenesis of psoriasis

Cell Immunol. 2018 Sep:331:16-21. doi: 10.1016/j.cellimm.2018.04.016. Epub 2018 May 2.

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor and the authors, following concerns raised in the public domain. The authors informed the journal that they had found that the psoriasis model panel and the vector panel of Fig 4D were duplicated. The authors think that the relevant results are not sufficient to support the conclusions drawn from this study.

Keywords: NF-κB p105/p50; NFKB1; Psoriasis; Th1; Th17.

Publication types

  • Research Support, Non-U.S. Gov't
  • Retracted Publication

MeSH terms

  • Adult
  • Animals
  • Cell Line
  • Cells, Cultured
  • Cytokines / blood
  • Cytokines / immunology
  • Cytokines / metabolism
  • Female
  • Humans
  • Imiquimod
  • Interleukin-17 / immunology*
  • Interleukin-17 / metabolism
  • Male
  • Mice, Inbred BALB C
  • Middle Aged
  • NF-kappa B p50 Subunit / genetics
  • NF-kappa B p50 Subunit / immunology*
  • NF-kappa B p50 Subunit / metabolism
  • Psoriasis / chemically induced
  • Psoriasis / immunology*
  • Psoriasis / metabolism
  • Skin / immunology
  • Skin / metabolism
  • Skin / pathology
  • Th1 Cells / immunology*
  • Th1 Cells / metabolism
  • Young Adult

Substances

  • Cytokines
  • IL17A protein, human
  • Interleukin-17
  • NF-kappa B p50 Subunit
  • NFKB1 protein, human
  • Imiquimod