Candidemia in the intensive care unit: A 12-year retrospective cohort study in Reunion Island

Med Mal Infect. 2018 Sep;48(6):414-418. doi: 10.1016/j.medmal.2018.04.392. Epub 2018 May 9.

Abstract

Objectives: We aimed to describe the epidemiology of Candida bloodstream infection in an intensive care unit (ICU) in Reunion Island.

Methods: We performed a retrospective cohort study and evaluated 63 candidemia episodes, which occurred between January 2004 and December 2015 in the ICU of a University Hospital in St-Pierre.

Results: The incidence rate of candidemia in the ICU was estimated at 7.6%. Candida albicans was the most common yeast pathogen species recovered (54%), followed by Candida glabrata (17%), Candida tropicalis (12%) and Candida parapsilosis (10%). Between 2012 and 2015, we also observed a modification of antifungal use.

Conclusion: The epidemiology of candidemia in Reunion Island is characterized by the predominance of Candida albicans and by the relative importance of Candida tropicalis. This pattern corresponds to a model of epidemiological transition between the one usually observed in tropical areas and the one observed in temperate countries.

Keywords: Candidemia; Candidémie; Intensive care unit; Reunion Island; Réanimation; Île de la Réunion.

MeSH terms

  • Candidemia / epidemiology*
  • Cohort Studies
  • Female
  • Humans
  • Incidence
  • Intensive Care Units
  • Male
  • Middle Aged
  • Retrospective Studies
  • Reunion / epidemiology
  • Time Factors