Recurrence rate of atrial fibrillation after the first clinical episode: A prospective evaluation using continuous cardiac rhythm monitoring

Clin Cardiol. 2018 May;41(5):594-600. doi: 10.1002/clc.22904. Epub 2018 May 14.

Abstract

Background: Decision making regarding a patient who has experienced a first clinical episode of atrial fibrillation (AF) is challenging, and the AF recurrences should be a significant consideration. Continuous long-term rhythm monitoring via implantable loop recorders (ILRs) has enabled us to evaluate the AF recurrence profile after the first clinical episode and to investigate clinical parameters associated with the course of the arrhythmia.

Hypothesis: Continuous rhythm monitoring via ILRs in AF patients after the first clinical episode is of clinical significance and precisely evaluate the AF recurrence profile.

Methods: Thirty consecutive patients with paroxysmal AF received an ILR after their first symptomatic episode. We evaluated the maximum duration of episodes and the recurrence rate of the arrhythmia during a follow-up period of 3 years.

Results: Three patients (10%) had no AF recurrence, whereas 4 patients (13.3%) presented only 1 episode. Almost half of the patients (46.7%) had a low recurrence rate (<5 episodes/year), whereas the majority of patients (19/30) suffered from episodes with maximum duration ≤24 hours. Eleven patients (36.7%) presented either no episode or a low recurrence rate with episodes lasting ≤24 hours. The use of statins was greater in patients with a low recurrence rate (P = 0.025).

Conclusions: A significant percentage of patients either suffer no AF recurrence after their first symptomatic episode or show a low recurrence rate. Most patients present episodes of short duration. If these findings are confirmed in larger studies, they could have clinical implications ensuring individualized management of the arrhythmia in the future.

Keywords: Anticoagulation; Arrhythmia; Atrial Fibrillation; Continuous Monitoring; Implantable Loop Recorder.

MeSH terms

  • Action Potentials
  • Aged
  • Atrial Fibrillation / diagnosis*
  • Atrial Fibrillation / physiopathology
  • Electrocardiography, Ambulatory / instrumentation
  • Electrocardiography, Ambulatory / methods*
  • Female
  • Heart Conduction System / physiopathology*
  • Heart Rate*
  • Humans
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Prospective Studies
  • Recurrence
  • Signal Processing, Computer-Assisted
  • Telemetry / instrumentation
  • Telemetry / methods*
  • Time Factors