OCT Angiography Helps Distinguish Between Proliferative Macular Telangiectasia Type 2 and Neovascular Age-Related Macular Degeneration

Ophthalmic Surg Lasers Imaging Retina. 2018 May 1;49(5):303-312. doi: 10.3928/23258160-20180501-03.

Abstract

Background and objective: To demonstrate the advantage of optical coherence tomography angiography (OCTA) for the diagnosis and management of proliferative macular telangiectasia type 2 (MacTel2) masquerading as neovascular age-related macular degeneration (AMD).

Patients and methods: This is an observational cases series. Three patients referred with the diagnosis of neovascular AMD were identified in this retrospective study. In addition to color fundus, fluorescein angiography, and spectral-domain OCT (SD-OCT) imaging, SD-OCTA (AngioPlex; Carl Zeiss Meditec, Dublin, CA) was performed.

Results: SD-OCTA revealed bilateral parafoveal retinal microvascular changes in three patients and unambiguously confirmed the diagnosis of MacTel2.

Conclusion: OCTA is an important tool for the correct diagnosis of MacTel2 in older patients with the concomitant or masquerading diagnosis of AMD. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:303-312.].

Publication types

  • Case Reports
  • Observational Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Choroidal Neovascularization / diagnosis*
  • Computed Tomography Angiography*
  • Diagnosis, Differential
  • Diagnostic Techniques, Ophthalmological*
  • Female
  • Humans
  • Macular Degeneration / diagnosis*
  • Male
  • Middle Aged
  • Retinal Telangiectasis / diagnostic imaging*
  • Tomography, Optical Coherence / methods*