Primary lymphoma of appendix presenting as acute appendicitis: A case report

Giuseppe Caristo; Guido Griseri; Rosario Fornaro; Antonio Langone; Angelo Franceschi; Veronica Errigo; Cecilia Ferrari; Marco Casaccia; Marco Frascio; Angelo Schirru

doi:10.1016/j.ijscr.2018.04.031

Primary lymphoma of appendix presenting as acute appendicitis: A case report

Int J Surg Case Rep. 2018:48:30-33. doi: 10.1016/j.ijscr.2018.04.031. Epub 2018 May 7.

Authors

Affiliations

¹ San Paolo Hospital, Via Genova 30, Savona, 17100, Italy. Electronic address: [email protected].
² San Paolo Hospital, Via Genova 30, Savona, 17100, Italy. Electronic address: [email protected].
³ University of study of Genoa (Italy), Policlinico San Martino Largo Benzi 10, 16132 Genova, Italy. Electronic address: [email protected].
⁴ San Paolo Hospital, Via Genova 30, Savona, 17100, Italy. Electronic address: [email protected].
⁵ San Paolo Hospital, Via Genova 30, Savona, 17100, Italy. Electronic address: [email protected].
⁶ San Paolo Hospital, Via Genova 30, Savona, 17100, Italy. Electronic address: [email protected].
⁷ San Paolo Hospital, Via Genova 30, Savona, 17100, Italy. Electronic address: [email protected].
⁸ University of study of Genoa (Italy), Policlinico San Martino Largo Benzi 10, 16132 Genova, Italy. Electronic address: [email protected].
⁹ University of study of Genoa (Italy), Policlinico San Martino Largo Benzi 10, 16132 Genova, Italy. Electronic address: [email protected].
¹⁰ San Paolo Hospital, Via Genova 30, Savona, 17100, Italy. Electronic address: [email protected].

Abstract

Introduction: Primary lymphomas of appendix are extremely rare tumors. The incidence is 0.015% of all gastrointestinal lymphomas.

Presentation of case: We present a case of a 75 year-old male patient who presented with acute abdominal pain in the lower right quadrant and fever.

Discussion: The patient received laparotomic appendectomy. The definitive histopathological examination revealed the presence of diffuse large cell B-lymphoma of the appendix. The neoplasms of appendix usually manifest clinically with sign and symptoms of acute appendicitis from luminal obstruction (30-50%). Preoperative diagnosis is difficult and often occurs through histopathological examination.

Conclusion: Primary appendiceal lymphoma is rare and there are no clear guidelines for therapy. Primary surgical resection followed by post-operative chemotherapy showed high efficacy. The histopathological examination of all appendectomy is essential.

Keywords: Acute appendicitis; Appendix; Case report; Lymphoma.