Analysis of Minimally Invasive Left Thoracotomy HVAD Implantation - A Single-Center Experience

Thorac Cardiovasc Surg. 2019 Apr;67(3):170-175. doi: 10.1055/s-0038-1649493. Epub 2018 May 27.

Abstract

Background: Minimally invasive left ventricular assist device (LVAD) implantation may reduce peri-/postoperative complications and risks associated with resternotomies. In this study, we describe our first results using a minimally invasive LVAD implantation technique (lateral thoracotomy [LT] group). These results were compared with LVAD implantations done via full median sternotomy (STX group).

Methods: HVAD (HeartWare, Framingham, Massachusetts, United States) implantations in 70 patients (LT group n = 22, 52 ± 15 years old; STX group n = 48, 59 ± 11 years old) were retrospectively analyzed. Minimally invasive access via left thoracotomy was feasible in 22 patients. Peri- and postoperative analyses of survival and adverse events were performed.

Results: No survival differences were observed between the LT and STX group (p = 0.43). LT patients without temporary right ventricular assist device (tRVAD) showed a significantly better survival rate compared to LT patients with concomitant tRVAD implantation (p = 0.02), which could not be demonstrated in the STX group (p = 0.11). Two LT and four STX patients were successfully bridged to heart transplantation and three STX patients were successfully weaned with subsequent LVAD explantations. LVAD-related infections (n = 4 LT group vs n = 20 STX group, p = 0.04) were less likely in the LT group. No wound dehiscence occurred in the LT group, whereas five were observed in the STX group (p = 0.17). The amount of perioperative blood transfusions (within the first 7 postoperative days) did not differ in both study groups (p = 0.48).

Conclusion: The minimally invasive approach is a viable alternative with the possibility to reduce complications and should be particularly considered for bridge-to-transplant patients.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Female
  • Germany
  • Heart Failure / diagnosis
  • Heart Failure / mortality
  • Heart Failure / physiopathology
  • Heart Failure / therapy*
  • Heart-Assist Devices*
  • Humans
  • Male
  • Middle Aged
  • Minimally Invasive Surgical Procedures
  • Postoperative Complications / etiology
  • Prosthesis Design
  • Prosthesis Implantation / adverse effects
  • Prosthesis Implantation / instrumentation*
  • Prosthesis Implantation / methods*
  • Prosthesis Implantation / mortality
  • Recovery of Function
  • Retrospective Studies
  • Sternotomy* / adverse effects
  • Sternotomy* / mortality
  • Thoracotomy / adverse effects
  • Thoracotomy / methods*
  • Thoracotomy / mortality
  • Time Factors
  • Treatment Outcome
  • Ventricular Function, Left*