Synthesis of lipid-black phosphorus quantum dot bilayer vesicles for near-infrared-controlled drug release

Chem Commun (Camb). 2018 Jun 8;54(47):6060-6063. doi: 10.1039/c8cc03423k.

Abstract

Black phosphorus quantum dots are incorporated into liposomal bilayers to produce a drug delivery system with excellent near-infrared (NIR) photothermal properties and drug release capability controlled by light. In vitro experiments demonstrate its good biocompatibility and NIR-light-induced chemo-photothermal antitumor efficiency.

MeSH terms

  • Animals
  • Antineoplastic Agents / pharmacology*
  • Cholesterol / chemistry
  • Cholesterol / toxicity
  • Doxorubicin / pharmacology*
  • Drug Liberation
  • Heating
  • Humans
  • Infrared Rays
  • Lipid Bilayers / chemistry*
  • Lipid Bilayers / toxicity
  • Liposomes / chemistry*
  • Liposomes / toxicity
  • MCF-7 Cells
  • Mice
  • Microscopy, Confocal
  • Particle Size
  • Phosphatidylcholines / chemistry
  • Phosphatidylcholines / toxicity
  • Phosphorus / chemistry*
  • Phosphorus / toxicity
  • Quantum Dots / chemistry
  • Quantum Dots / radiation effects*
  • Quantum Dots / toxicity

Substances

  • Antineoplastic Agents
  • Lipid Bilayers
  • Liposomes
  • Phosphatidylcholines
  • Phosphorus
  • Doxorubicin
  • Cholesterol