We present here a case report of recurring fainting due to orthostatic hypotension in a 45‑year-old woman with Hodgkin's' disease, treated by radiation therapy and resection of cervical lymph node. We discuss difficulties of identification of etiology and mechanisms of orthostatic hypotension as well as possible role of baroreflex failure at the background of the Hodgkin's' disease treatment, and vasovagal syncope of which the patient suffered in her youth.
Keywords: vasovagal syncope, orthostatic hypotension, baroreflex failure, active orthostatic test.