Few data on HIV incidence among men who have sex with men and inject drugs (MSM-PWID) are available. Drawing on a prospective cohort in Vancouver, Canada, we examined the relationship between MSM status and HIV incidence among PWID using Kaplan-Meier analyses and extended Cox regression. Data were collected from 1996 to 2014 and analyzed in 2017. Of 1131 HIV-negative male PWID, 8.6% (n = 97) reported sex with men over the study period. MSM status was crudely associated with HIV incidence [Hazard Ratio (HR) = 1.81; 95% CI 1.08-3.03], but not after adjustment for daily cocaine injection and syringe borrowing (Adjusted HR = 1.33; 95% CI 0.78-2.28). Findings highlight the need for harm reduction interventions and socio-behavioral research focused on MSM-PWID.
Keywords: HIV; Incidence; Injection drug use; Men who have sex with men.