Insights into recombination-like events leading to outbreaks in USA through a retrospective study of porcine epidemic diarrhea virus isolates from China

Lang Gong; Jie Li; Qingfeng Zhou; Ying Lin; Jianru Qin; Chunyi Xue; Yongchang Cao

doi:10.1016/j.meegid.2018.06.002

Insights into recombination-like events leading to outbreaks in USA through a retrospective study of porcine epidemic diarrhea virus isolates from China

Infect Genet Evol. 2018 Sep:63:216-218. doi: 10.1016/j.meegid.2018.06.002. Epub 2018 Jun 4.

Authors

Lang Gong¹, Jie Li², Qingfeng Zhou³, Ying Lin¹, Jianru Qin¹, Chunyi Xue¹, Yongchang Cao⁴

Affiliations

¹ State Key Laboratory of Biocontrol, Life Sciences School, Sun Yat-sen University, Guangzhou, China.
² State Key Laboratory of Biocontrol, Life Sciences School, Sun Yat-sen University, Guangzhou, China; Guangdong Wen's Foodstuffs Group Co., Ltd. Yunfu, China; School of Biology and Food Engineering, Changshu Institute of Technology, Suzhou, China.
³ Guangdong Wen's Foodstuffs Group Co., Ltd. Yunfu, China.
⁴ State Key Laboratory of Biocontrol, Life Sciences School, Sun Yat-sen University, Guangzhou, China. Electronic address: [email protected].

Abstract

In April 2013, severe porcine epidemic diarrhea (PED) outbreaks first appeared in USA, causing significant financial losses. To detect the geographic origin and timing of USA porcine epidemic diarrhea virus (PEDV) isolates, we conducted a retrospective study to isolate 19 PEDV strains from positive samples obtained prior to April 2013. The results of phylogenetic and recombination analyses showed that GDS10 strain shared a common ancestor with CO13 strain, which was obtained from a piglet with severe diarrhea in USA.

Keywords: Chinese isolate; Origin; Porcine epidemic diarrhea virus; Recombination.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
China / epidemiology
Coronavirus Infections / epidemiology
Coronavirus Infections / transmission
Coronavirus Infections / veterinary*
Coronavirus Infections / virology
Disease Outbreaks*
Epidemiological Monitoring / veterinary*
Feces / virology
Molecular Epidemiology
Phylogeny*
Porcine epidemic diarrhea virus / classification
Porcine epidemic diarrhea virus / genetics*
Porcine epidemic diarrhea virus / isolation & purification
Porcine epidemic diarrhea virus / pathogenicity
Recombination, Genetic
Retrospective Studies
Swine
Swine Diseases / epidemiology*
Swine Diseases / transmission
Swine Diseases / virology
United States / epidemiology