Nasal colonization with Streptococcus pneumoniae and Staphylococcus aureus among hospitalized patients with laboratory-confirmed influenza

Aaron Campigotto; Andrew E Simor; Allison McGeer; Alexander Kiss; Samira Mubareka

doi:10.1016/j.diagmicrobio.2018.05.007

Nasal colonization with Streptococcus pneumoniae and Staphylococcus aureus among hospitalized patients with laboratory-confirmed influenza

Diagn Microbiol Infect Dis. 2018 Oct;92(2):133-135. doi: 10.1016/j.diagmicrobio.2018.05.007. Epub 2018 Jun 5.

Authors

Aaron Campigotto¹, Andrew E Simor², Allison McGeer³, Alexander Kiss⁴, Samira Mubareka⁵

Affiliations

¹ London Health Sciences Centre, 800 Commissioners Road East, London, ON, N6A 5W9, Canada.
² Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, M5S 1A8, Canada; Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada.
³ Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, M5S 1A8, Canada; Mount Sinai Hospital, 600 University Avenue, Toronto, ON, M5G 1X5, Canada.
⁴ Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada.
⁵ Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, M5S 1A8, Canada; Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada. Electronic address: [email protected].

PMID: 29884564
DOI: 10.1016/j.diagmicrobio.2018.05.007

Abstract

Nasopharyngeal swabs from 148 adult patients with influenza were analyzed by polymerase chain reaction for Staphylococcus aureus and or Streptococcus pneumoniae. We found that patients colonized with S. pneumoniae were younger, had lower oxygen saturations, and were more likely to require admission to critical care.

Keywords: Coinfection; Influenza virus; Nasal colonization; Staphylococcus aureus; Streptococcus pneumoniae.

MeSH terms

Aged
Aged, 80 and over
Coinfection
Female
Humans
Influenza A virus / physiology*
Influenza, Human / complications*
Influenza, Human / virology
Male
Middle Aged
Nose / microbiology
Pneumococcal Infections / microbiology*
Staphylococcal Infections / microbiology*
Staphylococcus aureus / physiology*
Streptococcus pneumoniae / physiology*