Whole-genome resequencing reveals world-wide ancestry and adaptive introgression events of domesticated cattle in East Asia

Nat Commun. 2018 Jun 14;9(1):2337. doi: 10.1038/s41467-018-04737-0.

Abstract

Cattle domestication and the complex histories of East Asian cattle breeds warrant further investigation. Through analysing the genomes of 49 modern breeds and eight East Asian ancient samples, worldwide cattle are consistently classified into five continental groups based on Y-chromosome haplotypes and autosomal variants. We find that East Asian cattle populations are mainly composed of three distinct ancestries, including an earlier East Asian taurine ancestry that reached China at least ~3.9 kya, a later introduced Eurasian taurine ancestry, and a novel Chinese indicine ancestry that diverged from Indian indicine approximately 36.6-49.6 kya. We also report historic introgression events that helped domestic cattle from southern China and the Tibetan Plateau achieve rapid adaptation by acquiring ~2.93% and ~1.22% of their genomes from banteng and yak, respectively. Our findings provide new insights into the evolutionary history of cattle and the importance of introgression in adaptation of cattle to new environmental challenges in East Asia.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Breeding*
  • Cattle / genetics*
  • China
  • Chromosomes / ultrastructure
  • Domestication
  • Female
  • Genetic Variation
  • Genetics, Population*
  • Genome*
  • Geography
  • Haplotypes
  • Male
  • Mitochondria
  • Models, Statistical
  • Phylogeny
  • Polymorphism, Single Nucleotide
  • Species Specificity
  • Tibet