Immunological effect of silica dust analyzed by monoclonal antibodies

J Clin Lab Immunol. 1985 Apr;16(4):207-10.

Abstract

We found a significant decrease of OKT8 + ve cells in silicosis patients (18.1%), but also in unaffected exposed workers (19.0%), when compared with sex- and age-matched controls (22.8%). The proportion of OKT8 + ve cells was significantly lower in subjects with antinuclear antibodies (15.7%) and in those with IgG-rheumatoid factors (16.3%).

MeSH terms

  • Adult
  • Aged
  • Antibodies, Antinuclear / analysis
  • Antibodies, Monoclonal
  • Antigens, Differentiation, T-Lymphocyte
  • Antigens, Surface / analysis
  • Autoantibodies / immunology
  • Dust
  • Humans
  • Male
  • Middle Aged
  • Rheumatoid Factor / analysis
  • Silicon Dioxide
  • Silicosis / immunology*
  • T-Lymphocytes / classification
  • T-Lymphocytes / immunology*

Substances

  • Antibodies, Antinuclear
  • Antibodies, Monoclonal
  • Antigens, Differentiation, T-Lymphocyte
  • Antigens, Surface
  • Autoantibodies
  • Dust
  • Silicon Dioxide
  • Rheumatoid Factor