Testicular germ cell tumors. A review of 10 years' experience

Cancer. 1985 Sep 15;56(6):1251-6. doi: 10.1002/1097-0142(19850915)56:6<1251::aid-cncr2820560605>3.0.co;2-v.

Abstract

Experience with 200 cases of testicular tumors seen over a period of 10 years has been presented. Modes of presentation, response to treatment, and patterns of failure have been analyzed in 186 cases of germ cell tumors. The role of radiation in the overall management of seminomas is reaffirmed, and the need for adjuvant radiation to the supraclavicular region and mediastinum is demonstrated in Stage II cases of seminoma. Results of treatment with radiation alone or combined with chemotherapy were not encouraging in nonseminomas in the current series. The advantages of an aggressive multimodal approach with judicious combination of surgery, radiation treatment, and combination chemotherapy have been discussed, with review of relevant literature.

MeSH terms

  • Adolescent
  • Adult
  • Combined Modality Therapy
  • Dysgerminoma / therapy
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Neoplasms, Germ Cell and Embryonal / therapy*
  • Retrospective Studies
  • Teratoma / therapy
  • Testicular Neoplasms / therapy*