Abstract
Lasiodiplodia theobromae is a known plant pathogen in tropical and subtropical areas. Few cases have been reported in humans (usually keratitis and endophthalmitis) with only two cases of fungal sinusitis in immunocompromised and immunocompetent patients published to date. We report a case of invasive sinusitis secondary to L. theobromae in an allogeneic hematopoietic cell transplant recipient successfully treated with surgical debridement and triazole antifungals with a review of available literature.
Keywords:
Hematopoietic cell transplant; Lasiodiplodia theobromae; Sinusitis.
MeSH terms
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Antifungal Agents / administration & dosage
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Ascomycota / classification
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Ascomycota / isolation & purification*
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Debridement
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Hematopoietic Stem Cell Transplantation / adverse effects*
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Humans
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Invasive Fungal Infections / diagnosis*
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Invasive Fungal Infections / microbiology
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Invasive Fungal Infections / pathology
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Invasive Fungal Infections / therapy
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Male
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Middle Aged
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Rhinitis / diagnosis*
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Rhinitis / microbiology
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Rhinitis / pathology
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Rhinitis / therapy
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Sinusitis / diagnosis*
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Sinusitis / microbiology
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Sinusitis / pathology
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Sinusitis / therapy
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Transplant Recipients
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Transplantation, Homologous / adverse effects
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Treatment Outcome
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Triazoles / administration & dosage
Substances
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Antifungal Agents
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Triazoles