Keywords: ECP, extracorporeal photopheresis; EF, eosinophilic fasciitis; GDM, generalized deep morphea; HES, hypereosinophilic syndrome; IL, interleukin; JAK, Janus kinase; JAK-STAT; Janus kinase; Janus kinase inhibitor; ROM, range of motion; TGF-β, transforming growth factor beta; eosinophilic fasciitis; interleukin-4; morphea; tofacitinib; transforming growth factor-β.