Surgical site infection after primary total knee arthroplasty is associated with a longer duration of surgery

J Orthop Surg (Hong Kong). 2018 May-Aug;26(2):2309499018785647. doi: 10.1177/2309499018785647.

Abstract

Purpose: Surgical site infection (SSI) is a serious complication following total knee arthroplasty (TKA) leading to considerable morbidity. The incidence is reported to be up to 2%. Risk factors continue to be an area of intense debate. Our study aims to report the incidence of SSI and identify possible risk factors in our patients undergoing TKA.

Methods: Prospectively collected data for 905 patients who underwent elective unilateral TKA by a single surgeon from February 2004 to July 2014 were reviewed. Patient demographics and relevant co-morbidities such as diabetes and heart disease were analysed. The presence of superficial wound infections and/or prosthetic joint infections was included.

Results: The overall infection rate was 1.10% (10 of 905 patients). Six patients (0.66%) were diagnosed with superficial infections and four with PJI (0.44%). The mean operative duration for TKA with SSI was significantly longer at 90.5 ± 28.2 min, compared to 72.2 ± 20.3 min in TKA without SSI ( p = 0.03). All superficial infections occurred within the first month post-surgery and were self-limiting with oral antibiotics. The four patients with PJI required repeated procedures following TKA, including debridement, implant removal and/or revision arthroplasty. None of the 10 patients had a history of diabetes. There were no significant differences in demographics and co-morbidities between those who developed infection after TKA and those who did not.

Conclusion: An overwhelming majority had good outcomes with only four deep infections resulting in revision surgery. We report that the risk of infection in TKA was significantly associated with a longer operative duration.

Keywords: joint prosthesis; knee arthroplasty; postoperative complications; risk factors; sepsis/complications; soft tissue infections; surgical wound infection.

MeSH terms

  • Aged
  • Arthritis, Infectious / epidemiology*
  • Arthritis, Infectious / etiology
  • Arthroplasty, Replacement, Knee / adverse effects*
  • Female
  • Humans
  • Incidence
  • Male
  • Retrospective Studies
  • Risk Factors
  • Singapore / epidemiology
  • Surgical Wound Infection / epidemiology*
  • Surgical Wound Infection / etiology
  • Time Factors