Kawasaki disease has become the leading cause of acquired heart disease in children in North America and Japan. The incidence rate of Kawasaki disease varies significantly across regions and races. The first-degree relatives of patients with Kawasaki disease have a significantly higher risk of this disease than the general population. This article reviews the onset of familial Kawasaki disease and possible pathogenesis.
川崎病已成为北美和日本等地儿童获得性心脏病的主要原因。该病的发病率存在明显的地区和种族差异，患者的一级亲属罹患此病的风险较普通人群明显升高。该文回顾了近年来各地川崎病家庭发病的相关情况，并对其可能的发病机制进行综述。