Aortic Endograft Infection with Mycobacterium chimaera and Granulicatella adiacens, Switzerland, 2014

Emerg Infect Dis. 2018 Sep;24(9):1700-1704. doi: 10.3201/eid2409.180247. Epub 2018 Sep 17.

Abstract

We describe an aortic endograft infection caused by Mycobacterium chimaera and Granulicatella adiacens, successfully treated with prolonged antimicrobial drug therapy after complete explantation of the infected endoprosthesis and extra-anatomical reconstruction. Whole-genome sequencing analysis did not indicate a close relationship to bacterial strains known to cause infections after cardiac surgery.

Keywords: Granulicatella adiacens; Mycobacterium chimaera; Switzerland; abdominal aortic endograft infection; bacteria; cardiac surgery outbreak; nontuberculous mycobacteria; tuberculosis and other mycobacteria; whole genome sequencing.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Aorta, Abdominal
  • Aortic Aneurysm / surgery
  • Diagnosis, Differential
  • Humans
  • Male
  • Middle Aged
  • Mycobacterium Infections, Nontuberculous / diagnosis*
  • Mycobacterium Infections, Nontuberculous / drug therapy
  • Mycobacterium Infections, Nontuberculous / microbiology
  • Nontuberculous Mycobacteria / isolation & purification*
  • Postoperative Complications / diagnosis
  • Postoperative Complications / drug therapy
  • Postoperative Complications / microbiology
  • Prosthesis-Related Infections / diagnosis*
  • Prosthesis-Related Infections / drug therapy
  • Prosthesis-Related Infections / microbiology

Substances

  • Anti-Bacterial Agents