Role of FDG PET-CT in the treatment management of Hodgkin lymphoma

Cancer Radiother. 2018 Sep;22(5):393-400. doi: 10.1016/j.canrad.2018.06.001. Epub 2018 Jul 20.

Abstract

Fluorodeoxyglucose (FDG) positons emission tomography (PET)-computed tomography (CT) is used in many ways at baseline and during the treatment of patients with Hodgkin lymphoma. Many properties of the technique are used in the different steps of patient's management. Initial staging with PET-CT is more accurate than conventional imaging and PET-CT also became the gold standard imaging at the end of treatment with a negative PET-CT mandatory for reaching a complete remission. Early assessment of response by PET-CT is one of the most powerful prognostic factors for progression-free survival of patients with localized and advanced stages and allows guiding treatment. Conversely, previous studies showed that there is no role of FDG PET-CT for the patient's follow-up.

Keywords: Hodgkin lymphoma; Imagerie; Interim PET; Lymphome de Hogkin; PET-CT; TEP-scanographie.

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents / therapeutic use
  • Clinical Decision-Making*
  • Fluorodeoxyglucose F18
  • Hematopoietic Stem Cell Transplantation
  • Hodgkin Disease / diagnostic imaging*
  • Hodgkin Disease / therapy*
  • Humans
  • Lymph Nodes / diagnostic imaging*
  • Lymphatic Irradiation
  • Neoplasm Staging / methods
  • Neoplasm, Residual / diagnostic imaging
  • Positron Emission Tomography Computed Tomography*
  • Prognosis
  • Radiopharmaceuticals
  • Radiotherapy, Image-Guided

Substances

  • Antineoplastic Agents
  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18