Evaluation of potentially inappropriate medication utilization in elderly patients with cancer at outpatient oncology unit

J Oncol Pharm Pract. 2019 Sep;25(6):1321-1327. doi: 10.1177/1078155218788698. Epub 2018 Jul 25.

Abstract

Background: The aim of the study was to evaluate potentially inappropriate medication use in elderly patients with cancer.

Method: This study was conducted at outpatient oncology clinic from December 2014 to March 2015 among elderly cancer patients. Screening Tool of Older Person's Prescriptions/Screening Tool to Alert doctors to Right Treatment criteria were used to identify potentially inappropriate medication in elderly patients.

Results: Among 114 cancer patients 55.26% of them were male and the mean age of them was 71.78 ± 5.50 (years). The most common concurrent diseases were hypertension in 45 (39.47%) and diabetes in 26 (22.81%) patients. Polypharmacy (≥5 medications) was seen in 94.73% of them. Eighteen patients (15.79%) utilized medications inappropriately according to Screening Tool of Older Person's Prescriptions criteria. Medication omissions were identified in 112 patients (98.25%) with Screening Tool to Alert doctors to Right Treatment criteria.

Conclusions: Clinical pharmacists could improve the current prescribing practices in elderly patients with cancer by assessing potentially inappropriate medications.

Keywords: Geriatrics; clinical pharmacist; inappropriate medication; polypharmacy.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Antineoplastic Agents / therapeutic use
  • Diabetes Mellitus / drug therapy*
  • Female
  • Humans
  • Hypertension / complications
  • Hypertension / drug therapy*
  • Inappropriate Prescribing*
  • Male
  • Neoplasms / complications
  • Neoplasms / drug therapy*
  • Pharmacists*
  • Polypharmacy
  • Potentially Inappropriate Medication List
  • Practice Patterns, Physicians'
  • Professional Role*

Substances

  • Antineoplastic Agents