Careful consideration when responding to new data: dolutegravir and pregnancy

C Foster; S Fidler; Egh Lyall; Gpt Taylor

doi:10.1016/S2055-6640(20)30262-4

Careful consideration when responding to new data: dolutegravir and pregnancy

J Virus Erad. 2018 Jul 1;4(3):208. doi: 10.1016/S2055-6640(20)30262-4.

Authors

C Foster¹, S Fidler, Egh Lyall¹, Gpt Taylor

Affiliation

¹ Imperial College Healthcare NHS Trust, London, UK.

Abstract

This case highlights the current complexities of managing women in the early stages of pregnancy presenting on dolutegravir-based regimens. When responding to new data, there is an important decision to be made, between the potential, uncertain risk of teratogenicity against the potential increased risk of in utero vertical transmission of HIV-1.

Keywords: dolutegravir, pregnancy, treatment switch.

Publication types

Editorial