Author Correction: BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation

Simon Raffel; Mattia Falcone; Niclas Kneisel; Jenny Hansson; Wei Wang; Christoph Lutz; Lars Bullinger; Gernot Poschet; Yannic Nonnenmacher; Andrea Barnert; Carsten Bahr; Petra Zeisberger; Adriana Przybylla; Markus Sohn; Martje Tönjes; Ayelet Erez; Lital Adler; Patrizia Jensen; Claudia Scholl; Stefan Fröhling; Sibylle Cocciardi; Patrick Wuchter; Christian Thiede; Anne Flörcken; Jörg Westermann; Gerhard Ehninger; Peter Lichter; Karsten Hiller; Rüdiger Hell; Carl Herrmann; Anthony D Ho; Jeroen Krijgsveld; Bernhard Radlwimmer; Andreas Trumpp

doi:10.1038/s41586-018-0403-9

Author Correction: BCAT1 restricts αKG levels in AML stem cells leading to IDH^mut-like DNA hypermethylation

Nature. 2018 Aug;560(7718):E28. doi: 10.1038/s41586-018-0403-9.

Authors

Simon Raffel^{1

2

3}, Mattia Falcone^{1

2}, Niclas Kneisel⁴, Jenny Hansson⁵, Wei Wang⁴, Christoph Lutz³, Lars Bullinger⁶, Gernot Poschet⁷, Yannic Nonnenmacher^{8

9}, Andrea Barnert^{1

2}, Carsten Bahr^{1

2}, Petra Zeisberger^{1

2}, Adriana Przybylla^{1

2}, Markus Sohn^{1

2}, Martje Tönjes⁴, Ayelet Erez¹⁰, Lital Adler¹⁰, Patrizia Jensen¹¹, Claudia Scholl^{12

13}, Stefan Fröhling^{11

14

13}, Sibylle Cocciardi⁶, Patrick Wuchter^{3

15}, Christian Thiede¹⁶, Anne Flörcken¹⁷, Jörg Westermann¹⁷, Gerhard Ehninger¹⁶, Peter Lichter^{4

13}, Karsten Hiller^{8

9}, Rüdiger Hell⁷, Carl Herrmann^{18

19}, Anthony D Ho³, Jeroen Krijgsveld⁵, Bernhard Radlwimmer^{20

21}, Andreas Trumpp^{22

23

24}

Affiliations

¹ Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), 69120, Heidelberg, Germany.
² Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ) and DKFZ-ZMBH Alliance, 69120, Heidelberg, Germany.
³ Department of Internal Medicine V, Heidelberg University Hospital, 69120, Heidelberg, Germany.
⁴ Division of Molecular Genetics, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.
⁵ Genome Biology Unit, European Molecular Biology Laboratory (EMBL), 69117, Heidelberg, Germany.
⁶ Department of Internal Medicine III, University Hospital Ulm, 89081, Ulm, Germany.
⁷ Centre for Organismal Studies (COS), University of Heidelberg, 69120, Heidelberg, Germany.
⁸ Department of Bioinfomatics and Biochemistry and Braunschweig Integrated Center of Systems Biology (BRICS), Technical University Braunschweig, 38106, Braunschweig, Germany.
⁹ Luxemburg Centre for Systems Biomedicine, University of Luxemburg, L-4367, Belvaux, Luxembourg.
¹⁰ Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel.
¹¹ Department of Translational Oncology, National Center for Tumor Diseases (NCT) Heidelberg and German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.
¹² Division of Applied Functional Genomics, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.
¹³ German Cancer Consortium (DKTK), DKFZ, 69120, Heidelberg, Germany.
¹⁴ Section for Personalized Oncology, Heidelberg University Hospital, 69120, Heidelberg, Germany.
¹⁵ Institute of Transfusion Medicine and Immunology Mannheim, Medical Faculty Mannheim, Heidelberg University, German Red Cross Blood Service Baden-Württemberg-Hessen, 68167, Mannheim, Germany.
¹⁶ Medical Department 1, University Hospital Carl Gustav Carus, 01307, Dresden, Germany.
¹⁷ Department of Hematology, Oncology and Tumor Immunology; Charité-University Medicine Berlin, Campus Virchow Klinikum, 13353, Berlin, Germany.
¹⁸ Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.
¹⁹ Institute of Pharmacy and Molecular Biotechnology, and Bioquant Center, University of Heidelberg, 69120, Heidelberg, Germany.
²⁰ Division of Molecular Genetics, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany. [email protected].
²¹ German Cancer Consortium (DKTK), DKFZ, 69120, Heidelberg, Germany. [email protected].
²² Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), 69120, Heidelberg, Germany. [email protected].
²³ Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ) and DKFZ-ZMBH Alliance, 69120, Heidelberg, Germany. [email protected].
²⁴ German Cancer Consortium (DKTK), DKFZ, 69120, Heidelberg, Germany. [email protected].

PMID: 30069041
DOI: 10.1038/s41586-018-0403-9

Abstract

In Extended Data Fig. 1a of this Letter, the flow cytometry plot depicting the surface phenotype of AML sample DD08 was a duplicate of the plot for AML sample DD06. Supplementary Data 4 has been added to the Supplementary Information of the original Letter to clarify the proteome data acquisition and presentation. The original Letter has been corrected online.

Publication types

Published Erratum