Incentives Boost Model-Based Control Across a Range of Severity on Several Psychiatric Constructs

Biol Psychiatry. 2019 Mar 1;85(5):425-433. doi: 10.1016/j.biopsych.2018.06.018. Epub 2018 Jul 2.

Abstract

Background: Human decision making exhibits a mixture of model-based and model-free control. Recent evidence indicates that arbitration between these two modes of control ("metacontrol") is based on their relative costs and benefits. While model-based control may increase accuracy, it requires greater computational resources, so people invoke model-based control only when potential rewards exceed those of model-free control. We used a sequential decision task, while concurrently manipulating performance incentives, to ask if symptoms and traits of psychopathology decrease or increase model-based control in response to incentives.

Methods: We recruited a nonpatient population of 839 online participants using Amazon Mechanical Turk who completed transdiagnostic self-report measures encompassing symptoms, traits, and factors. We fit a dual-controller reinforcement learning model and obtained a computational measure of model-based control separately for small incentives and large incentives.

Results: None of the constructs were related to a failure of large incentives to boost model-based control. In fact, for the sensation seeking trait and anxious-depression factor, higher scores were associated with a larger incentive effect, whereby greater levels of these constructs were associated with larger increases in model-based control. Many constructs showed decreases in model-based control as a function of severity, but a social withdrawal factor was positively correlated; alcohol use and social anxiety were unrelated to model-based control.

Conclusions: Our results demonstrate that model-based control can reliably be improved independent of construct severity for most measures. This suggests that incentives may be a useful intervention for boosting model-based control across a range of symptom and trait severity.

Keywords: Computational psychiatry; Habits and goals; Incentives; Model-based control; Psychiatric constructs; Reinforcement learning.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Decision Making*
  • Female
  • Humans
  • Male
  • Mental Disorders / psychology*
  • Middle Aged
  • Models, Psychological*
  • Motivation
  • Reinforcement, Psychology
  • Self Report
  • Self-Control / psychology*
  • Young Adult