[Role of radiation therapy in the management of pancreatic cancer]

Cancer Radiother. 2018 Oct;22(6-7):552-557. doi: 10.1016/j.canrad.2018.06.005. Epub 2018 Aug 9.
[Article in French]

Abstract

At diagnosis, about 15% of patients with pancreatic cancer present with a resectable tumour, 50% have a metastatic tumour, and 25% a locally advanced tumor (non-metastatic but unresectable due to vascular invasion) or borderline resectable. Despite the technical progress made in the field of radiation therapy and the improvement of the efficacy of chemotherapy, the prognosis of these patients remains very poor. Recently, the role of radiation therapy in the management of pancreatic cancer has been much debated. This review aims to evaluate the role of radiation therapy for these patients.

Keywords: Adénocarcinome du pancréas; Borderline; Chemoradiotherapy; Chimioradiothérapie; Folfirinox; Gemcitabine; Localement avancé; Locally advanced; Pancreatic adenocarcinoma; Radiation therapy; Radiothérapie.

Publication types

  • Review

MeSH terms

  • Humans
  • Pancreatic Neoplasms / pathology
  • Pancreatic Neoplasms / radiotherapy*