Breast Cancer Collaborative Registry informs understanding of factors predicting sleep quality

Support Care Cancer. 2019 Apr;27(4):1365-1373. doi: 10.1007/s00520-018-4417-5. Epub 2018 Aug 15.

Abstract

Significance: Poor sleep quality is a common and persistent problem reported by women with breast cancer (BC). Empirical evidence identifies many risk factors for self-reported sleep deficiency, but inconsistencies limit translation to practice.

Purpose: To increase understanding of risk factors predicting self-reported poor sleep quality in women with BC who completed the Breast Cancer Collaborative Registry (BCCR) questionnaire.

Methods: This cross-sectional study recruited women with a first diagnosis of BC (n = 1302) at five sites in Nebraska and South Dakota. Women completed the BCCR that includes numerous variables as well as the Pittsburgh Sleep Quality Index (PSQI) and SF36v2 (n = 1260). Descriptive statistics and non-parametric correlations were used to determine associations and create predictive models of sleep quality with BCCR variables and SF36v2 subscales.

Results: Most women were white (93.7%) and married (71.5%); mean age was 60.1 (21-90) years. Poor sleep was self-reported by 53% of women. Seven variables were highly associated with sleep quality (p ≤ 0.001). The first model found younger age, lower physical activity, and higher fatigue were the strongest combined and independent variables predicting poor sleep quality (F = 23.0 (p < .001), R2 = 0.103). Participants self-reported lower health status on most SF36v2 subscales [Z = 44.9 (11.6) to 49.1 (10.1)]. A second model found that all subscales were predictors of poor sleep; vitality, mental health, bodily pain, and general health were the strongest predictors (F = 101.3 (p < .001), R2 = 0.26).

Conclusions: Results confirm previously identified risk factors and reveal inconsistencies in other variables. Clinicians need to routinely screen for the identified risk factors of self-reported poor sleep quality.

Keywords: Mental health; Physical health; Quality of life; Sleep deficiency; Sleep quality; Symptoms.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Breast Neoplasms / complications
  • Breast Neoplasms / physiopathology*
  • Breast Neoplasms / psychology
  • Cancer Pain / complications*
  • Cancer Pain / physiopathology*
  • Cancer Pain / psychology
  • Cross-Sectional Studies
  • Fatigue / etiology
  • Fatigue / psychology
  • Female
  • Humans
  • Middle Aged
  • Quality of Life
  • Registries*
  • Self Report
  • Sleep / physiology*
  • Sleep Wake Disorders / etiology*
  • Sleep Wake Disorders / physiopathology*
  • Sleep Wake Disorders / psychology
  • Surveys and Questionnaires
  • Young Adult