1 Université Catholique de Louvain, Laboratory of Organic and Medicinal Chemistry, Bâtiment Lavoisier, Place Louis Pasteur 1 bte L4.01.02., B-1348 Louvain-la-Neuve, Belgium.
2 Department of Pharmaceutical, Chemical and Environmental Sciences, Faculty of Engineering and Science, University of Greenwich, Central Avenue, Chatham Maritime, ME4 4TB, UK. [email protected].
A new, green, safe, cost-effective and highly efficient electrochemical approach for the methoxymethylation of alcohols and phenols was successfully developed. The methodology was also applied to the synthesis of substituted acetals.