Breaking the frontiers of cosmetology with antimicrobial peptides

Biotechnol Adv. 2018 Dec;36(8):2019-2031. doi: 10.1016/j.biotechadv.2018.08.005. Epub 2018 Aug 14.

Abstract

Antimicrobial peptides (AMPs) are mostly endogenous, cationic, amphipathic polypeptides, produced by many natural sources. Recently, many biological functions beyond antimicrobial activity have been attributed to AMPs, and some of these have attracted the attention of the cosmetics industry. AMPs have revealed antioxidant, self-renewal and pro-collagen effects, which are desirable in anti-aging cosmetics. Additionally, AMPs may also be customized to act on specific cellular targets. Here, we review the recent literature that highlights the many possibilities presented by AMPs, focusing on the relevance and impact that this potentially novel class of active cosmetic ingredients might have in the near future, creating new market outlooks for the cosmetic industry with these molecules as a viable alternative to conventional cosmetics.

Keywords: Antimicrobial peptides; Cosmetics; Skincare.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anti-Infective Agents*
  • Antimicrobial Cationic Peptides*
  • Cosmetics*

Substances

  • Anti-Infective Agents
  • Antimicrobial Cationic Peptides
  • Cosmetics