Deletion of One 23S rRNA Gene (rrl) Copy Contributes to the Development of Linezolid Resistance in Staphylococcus warneri

Antimicrob Agents Chemother. 2018 Oct 24;62(11):e01139-18. doi: 10.1128/AAC.01139-18. Print 2018 Nov.

Authors

Caroline Rouard^{1

2}, Florence Doucet-Populaire^{3

2}, Christelle Guillet-Caruba¹, Millie Villet¹, Nadège Bourgeois-Nicolaos^{1

2}

Affiliations

¹ AP-HP, Hôpital Antoine Béclère, Service de Bactériologie-Hygiène, Clamart, France.
² EA4043, Bactéries Pathogènes et Santé, Faculté de Pharmacie, Université Paris Saclay, Chatenay-Malabry, France.
³ AP-HP, Hôpital Antoine Béclère, Service de Bactériologie-Hygiène, Clamart, France [email protected].

No abstract available

Keywords: Staphylococcus warneri; coagulase-negative staphylococci; drug resistance mechanisms; linezolid; oxazolidinones; ribosomes.

Publication types

Letter

MeSH terms

Anti-Bacterial Agents / pharmacology*
Drug Resistance, Bacterial / genetics*
Genes, rRNA / genetics*
Humans
Linezolid / pharmacology*
Microbial Sensitivity Tests / methods
RNA, Ribosomal, 23S / genetics*
Staphylococcal Infections / drug therapy
Staphylococcal Infections / microbiology
Staphylococcus / drug effects*
Staphylococcus / genetics*

Substances

Anti-Bacterial Agents
RNA, Ribosomal, 23S
Linezolid