A novel allergen-specific therapy with CD40-silenced B cells and dendritic cells

J Allergy Clin Immunol. 2018 Dec;142(6):1994-1997.e8. doi: 10.1016/j.jaci.2018.07.031. Epub 2018 Aug 23.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adjuvants, Immunologic / pharmacology
  • Allergens / pharmacology
  • Aluminum Hydroxide / pharmacology
  • Animals
  • B-Lymphocytes / immunology*
  • B-Lymphocytes / transplantation
  • Bronchoalveolar Lavage Fluid / cytology
  • CD40 Antigens / genetics*
  • Cytokines / immunology
  • Dendritic Cells / immunology
  • Hemocyanins / pharmacology
  • Immunoglobulin E / blood
  • Immunoglobulin G / blood
  • Immunotherapy, Adoptive
  • Male
  • Mice, Inbred BALB C
  • Ovalbumin / pharmacology
  • RNA, Small Interfering / genetics
  • Rhinitis, Allergic / blood
  • Rhinitis, Allergic / immunology
  • Rhinitis, Allergic / therapy*
  • Spleen / immunology

Substances

  • Adjuvants, Immunologic
  • Allergens
  • CD40 Antigens
  • Cytokines
  • Immunoglobulin G
  • RNA, Small Interfering
  • Immunoglobulin E
  • Aluminum Hydroxide
  • Ovalbumin
  • Hemocyanins
  • keyhole-limpet hemocyanin